Accelerated Cultivation of Peyote Graphed on Trichocereus

Propagation occurs chiefly through the seeds. The seeds need only be pressed lightly into sandy or clayey cactus soil and moistened a little each day. Germination may take several weeks. Because the seedlings are very small, they are easily over-looked. Overly heavy watering may wash them away and consequently hamper their growth. The seeds can be planted throughout the year. The cactus does not tolerate any frost.
Peyote requires a porous, clayey soil rich in minerals and nutrients. Apart from this, it is not demanding and will survive even some withering. In the summer, it should be exposed to the sun and watered in moderation, but never kept moist. It requires almost no water in the winter.
After a five-year growing period, a peyote cactus is large enough to be harvested for use. In time, the stump will grow new heads. Peyote is one of the slowest growing of all cacti. There is, however, a gardening technique for accelerating its growth:

Since peyote grows so slowly, one can quadruple the growth rate by splicing a button to a similar diameter limb of a T[richocerus] pachanoi or any other Trichocereus. This is done by carefully cutting each surface perfectly flat and smooth before grafting them. Until the graft takes, the peyote button may be held to the surfact of the Trichocerus by spreading multiple strings with small weights attached to them across the top of the button. A light ring of petroleum jelly should be painted around the cut to prevent desiccation of the contacting surfaces.
In four years the button will be very large. It may then be cut off, re-rooted and returned to the soil.

-p. 328, The Encyclopedia of Psychoactive Plants: Ethnopharmacology and Its Applications by Christian Rätsch (1998)

Related Reading

Peyote

Mann Research Laboratories Mescaline Hydrochloride Bottle

Merck's Mescaline Sulfate Bottle