Beta- Phenethylamines

Beta- Phenethylamines

Other names: B-phenethylamines, PEAs, 2-phenethylamines

B-phenethylamines are derivatives of phenethylamines. The biogenic 2-phenethylamine (PEA) dilates the blood vessles in the brain and consequently can, under certain circumstances, cause headaches or migraines. The most well-known psychoactive B-phenethylamine is mescaline, a component of numerous cacti.
Many cacti (including Gymnocactusspp. and Optuntia spp.) contain phenethylamines that are structurally very similar to mescaline but whose effects are practically unknown. It is quite possible that such substances as candicine (Trichocereus spp.), hodenine (Ariocarpus spp., Opuntia clavata Eng.; cf. Meyer et al. 1980 and Vanderveen et al. 1974) and macromerine (Coryphantha spp.) produce psychoactive effects when used at the appropriate dosages. This area still offers many opportunities for experimental human pharmacology (Heffter technique)… The genus Lobivia also contains hordenine (Follas et al. 1977)…
Numerous phenethylamines that have psychoactive effects (both empthogenic and/or psychedelic) have been synthesized (e.g., MDMA, MDA, MMDA, MDE, 2-CB, et cetra; cf. Shulgin and Shulgin 1991).

-page 816, The Encyclopedia of Psychoactive Plants: Enthnopharmacology and Its Applications by Christian Ratsch (1998)


Beta- Phenethylamine