Lead with Opium

Lead is used in therapeutics only for its astringent action. The acetate is prescribed internally in diarrhoea, generally along with opium and always in pill form, as the solution would at on the stomach and have less effect on the bowel. It has been tried in dysentery and cholera, but has proved of little value. Lead has also been advised in cases of haemorrhages from the lungs, kidneys and uterus, but is quite valueless here, as it acts as a styptic only when applied locally. Still less reason is there for its use in nephritis, cystitis and similar conditions.

Externally, a solution of acetate or the dilute solution of the subacetate is used as an astringent lotion in burns and as an injection in gonorrehea. White lead has been advised as a dusting powder in burns and skin affections, but is not superior in any way to other similiar preparations, and is liable to be absorbed. Nitrate of lead as a reputation in the treatment of onychia.

Lead ought not to be employed externally or internally except for a short time as otherwise symptoms of poisoning may arise.

- p. 678 , A Textbook of Pharmacology and Therapeutics on the Action of Drugs in Health and Disease by Dr. Arthur R. Cushny (1906)

Lead with Opium 1
Lead with Opium 2