Mrs. Winslow's Soothing Syrup

"ADVICE TO MOTHERS!—Are you broken in your rest by a sick
child suffering with the pain of cutting teeth? Go at once to a
chemist and get a bottle of MRS. WINSLOW’S SOOTHING SYRUP.
It will relieve the poor sufferer immediately. It is perfectly
harmless and pleasant to taste, it produces natural quiet sleep,
by relieving the child from pain, and the little cherub awakes “as
bright as a button.” It soothes the child, it softens the
gums, allays all pain, relieves wind, regulates the bowels,
and is the best known remedy for dysentery and diarrhoea,
whether arising from teething or other causes. Mrs. Winslow’s
Soothing Syrup is sold by Medicine dealers everywhere at 1s. 1½d.
per bottle. Manufactured in New York and at 498, Oxford-
street, London." -The Hampshire Telegraph and Sussex Chronicle, Saturday 9th January 1875

"Of the soothing syrups, none reached the success attained by the American product Mrs. Winslow's. Sold from 1830 until at least 1910, this potent teething elixir was made from sugar syrup, fennel, anise, caraway, alcohol and morphine sulfate. Nostrums (1911) attributed a number of deaths to the potion for the years 1906-10" (pp. 109- 110, in the Arms of Morpheus by Barbara Hodgson (2001)

Paracetamol (q.v.) can be of help in certain situations but, even in a verbal child, it has proved difficult to establish just how good it is at easing immediate postoperative pain. It does not do much to counteract serious pain. Here there is still no substitute for opiate analgesia. Unfortunately all the opiate drugs can, on occasion, cause serious respiratory depression. As a result doctors tended to ignore the whole issue of pain relief until such time as they became confident enough to say “this child needs morphine so, in order to be sure of giving an adequate dose, I will provide artificial respiratory support.” Even now, after 25 years of study, it is still difficult to be sure what the right dose is. - Neonatal Formulary 5