Cymbalta Duloxetine

Cymbalta (duloxetine) is unlike the selective serotonin reuptake inhibitor (SSRI) antidepressant such as Prozac (fluxetine), which are relatively serotonin- specific in action. Cymbalta has a dual mechanism of action. Presumably, it works by altering the neurotransmission of both serotonin and norepinephrine, two important neurotransmitters in the brain. ...
Cymbalta was originally approved by the U.S. Food and Drug Administration (FDA) for the treatment of major depression and management of pain and abnormal sensations caused by complications of diabetes mellitus... It is now approved also for treatment of generalized pain and sensitivity to touch. The use of a medication for its approved indications is called its labeled use. In clinical practice, however, physicians often prescribe medication for unlabeled ("off-label") uses when published clinical studies, case reports, or their own clinical experiences support the efficacy and safety of those treatments. Physcians may use Cymbalta "off-label" to treat other pain conditions, panic disorder, posttraumatic stress disorder, social phobia and urinary difficulties (incontinence). ...
The most common side effects reported with Cymbalta are nausea, vomiting, constipation, dry mouth, dizziness, increased sweating (e.g. night sweats), fatigue and insomnia. ...
Sexual side effects, including delayed orgasm in women and retarded ejaculatoin in men occur with Cymbalta at about the same rate as with the SNRI antidepressent Effexor. - pages 105- 106
What Your Patients Need to Know about Psychiatric Medications By Robert H. Chew et. all

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Cymbalta Duloxetine
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